Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8391893 | 0.74 | — | — | |
| SCHEMBL3555319 | 0.72 | — | — | |
| SCHEMBL3553040 | 0.72 | — | — | |
| SCHEMBL27875672 | 0.71 | FDPS (0.36) | TSHRLMNATHRBFDPS | |
| SCHEMBL11664072 | 0.70 | — | — | |
| SCHEMBL27756430 | 0.69 | TSHR (0.39) | TSHRLMNATHRBFDPS | |
| SCHEMBL5707079 | 0.67 | TSHR (0.38) | TSHRLMNA | |
| SCHEMBL11170814 | 0.67 | TSHR (0.38) | TSHRLMNAFDPS | |
| SCHEMBL20621393 | 0.67 | TSHR (0.32) | TSHRLMNA | |
| SCHEMBL15971610 | 0.67 | TSHR (0.38) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935230-B1 | HERBICIDALLY ACTIVE CYCLIC DIONE COMPOUNDS, OR DERIVATIVES THEREOF, SUBSTITUTED BY A PHENYL WHICH HAS AN ALKYNYL-CONTAINING SUBSTITUENT | SYNGENTA LTD (GB) | 2018-01-17 | — | — | EP | disclosed |
| US-9615577-B2 | Herbicidally active cyclic dione compounds, or derivatives therefor, substituted by a phenyl which has an alkynyl-containing substituent | SYNGENTA LIMITED (GB) | 2017-04-11 | — | — | US | disclosed |
| US-20150342185-A1 | HERBICIDALLY ACTIVE CYCLIC DIONE COMPOUNDS, OR DERIVATIVES THEREFOR, SUBSTITUTED BY A PHENYL WHICH HAS AN ALKYNYL-CONTAINING SUBSTITUENT | SYNGENTA LIMITED (CH) | 2015-12-03 | — | — | US | disclosed |
| EP-2935230-A2 | HERBICIDALLY ACTIVE CYCLIC DIONE COMPOUNDS, OR DERIVATIVES THEREOF, SUBSTITUTED BY A PHENYL WHICH HAS AN ALKYNYL-CONTAINING SUBSTITUENT | Syngenta Limited (GB) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014096289-A2 | HERBICIDALLY ACTIVE CYCLIC DIONE COMPOUNDS, OR DERIVATIVES THEREOF, SUBSTITUTED BY A PHENYL WHICH HAS AN ALKYNYL-CONTAINING SUBSTITUENT | SYNGENTA LIMITED (GB) | 2014-06-26 | — | — | WO | disclosed |
| EP-0695184-B1 | HIV PROTEASE INHIBITORS | AGOURON PHARMA (US) | 1999-04-21 | — | — | EP | disclosed |
| US-5863950-A | AMIDES OR THIO AMIDE COMPOUNDS WITH HYDROXY OR ETHER GROUPS | AGOURON PHARMACEUTICALS, INC. (US) | 1999-01-26 | — | — | US | disclosed |
| US-5714518-A | HIV protease inhibitors and methods of making the same | AGOURON PHARMACEUTICALS (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0695184-A4 | HIV PROTEASE INHIBITORS | AGOURON PHARMA (US) | 1996-05-22 | — | — | EP | disclosed |
| EP-0695184-A1 | HIV PROTEASE INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 1996-02-07 | — | — | EP | disclosed |
| WO-1994015906-A1 | HIV PROTEASE INHIBITORS AND THEIR PREPARATION | AGOURON PHARMACEUTICALS, INC. (US) | 1994-07-21 | — | — | WO | disclosed |
| WO-1994015608-A1 | HIV PROTEASE INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 1994-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150342185-A1 | HERBICIDALLY ACTIVE CYCLIC DIONE COMPOUNDS, OR DERIVATIVES THEREFOR, SUBSTITUTED BY A PHENYL WHICH HAS AN ALKYNYL-CONTAINING SUBSTITUENT | CBR3, WEE1, NOTUM | TSHR 1133/4885LMNA 4265/4885THRB 2464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.