Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7134591 | 0.81 | PLA2G10 (0.83) | PLA2G10PLA2G2APARP10CYP17A1KMT2A | |
| SCHEMBL1032852 | 0.81 | PLA2G10 (0.52) | PLA2G10PLA2G2APARP10CYP17A1KMT2A | |
| SCHEMBL1446320 | 0.81 | PRSS1 (0.57) | — | |
| SCHEMBL6538715 | 0.80 | ALDH1A1 (0.56) | KMT2AALDH1A1TSHRPOLBMAPT | |
| SCHEMBL27263454 | 0.78 | KMT2A (0.68) | KMT2ATSHRPOLBMAPTHSD17B10 | |
| SCHEMBL11139354 | 0.78 | CYP3A4 (0.42) | KMT2AALDH1A1TSHRCYP3A4HSD17B10 | |
| SCHEMBL10777359 | 0.76 | PARP1 (0.50) | PLA2G10PLA2G2APARP10KMT2APARP15 | |
| SCHEMBL2861358 | 0.76 | PLA2G10 (0.55) | PLA2G10PLA2G2APARP10CYP17A1KMT2A | |
| Terephthalamide SCHEMBL23774 | 0.75 | PARP1 (0.71) | PLA2G10PLA2G2APARP10KMT2APARP4 | |
| SCHEMBL7176156 | 0.75 | ALDH1A1 (0.56) | PLA2G10PLA2G2AKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018764-A1 | DIHYDROBENZOANTHRACENONE, -PYRIMIDINONE OR DIHYDRONAPHTOQUINOLINONE | MERCK PATENT GMBH (DE) | 1998-05-07 | — | — | WO | disclosed |
| US-4458071-A | Process for 1-oxa-β-lactams | ELI LILLY AND COMPANY (US) | 1984-07-03 | — | — | US | disclosed |
| EP-0109302-A1 | Process for 1-oxa-beta-lactams | ELI LILLY AND COMPANY (US) | 1984-05-23 | — | — | EP | disclosed |