Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.44 |
| ▸ | AHR | P35869 | 2/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273244 | 1.00 | PTPN1 (0.50) | PTPN1APPRELACHRNA7AHR | |
| SCHEMBL7273249 | 1.00 | PTPN1 (0.50) | PTPN1APPRELACHRNA7AHR | |
| SCHEMBL20024736 | 0.89 | RELA (0.58) | PTPN1APPRELACHRNA7AHR | |
| SCHEMBL2095126 | 0.84 | AHR (0.60) | PTPN1RELACHRNA7AHRMAPT | |
| SCHEMBL6201488 | 0.84 | PTGS1 (0.57) | PTPN1RELACHRNA7AHRMAPT | |
| SCHEMBL6201486 | 0.84 | PTGS1 (0.57) | PTPN1RELACHRNA7AHRMAPT | |
| SCHEMBL74416 | 0.83 | RELA (0.66) | RELAAHRMAPTKDM4EALDH1A1 | |
| SCHEMBL74415 | 0.83 | RELA (0.66) | RELAAHRMAPTKDM4EALDH1A1 | |
| SCHEMBL15250570 | 0.83 | CHRNB4 (0.60) | APPRELACHRNA7AHRMAPT | |
| SCHEMBL501848 | 0.82 | CHRNA7 (0.60) | PTPN1APPRELACHRNA7NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0145434-A2 | Novel dihydropyridine derivatives and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |