Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 17/20 | 0.81 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.81 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.81 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.81 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296788 | 0.90 | PDE4A (0.82) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL7361518 | 0.90 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7362901 | 0.90 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7358081 | 0.90 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14412972 | 0.88 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL7364241 | 0.86 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL7366334 | 0.84 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL7359594 | 0.83 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL7366886 | 0.83 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7448224 | 0.81 | PDE4A (0.83) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992019594-A1 | PYRROLIDINONES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-11-12 | — | — | WO | disclosed |