Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.59 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13757755 | 0.90 | GPR119 (0.58) | GPR119TGFBR1LMNAMAPTALDH1A1 | |
| SCHEMBL27035718 | 0.89 | GPR119 (0.65) | GPR119TGFBR1LMNAMAPTKDM4E | |
| SCHEMBL4504053 | 0.89 | GPR119 (0.60) | GPR119TGFBR1LMNAMAPTKDM4E | |
| SCHEMBL4515782 | 0.88 | GPR119 (0.74) | GPR119TGFBR1LMNAMAPTKDM4E | |
| SCHEMBL4509519 | 0.88 | GPR119 (0.58) | GPR119TGFBR1DRD2DRD3 | |
| SCHEMBL13757744 | 0.87 | GPR119 (0.55) | GPR119TGFBR1LMNAMAPTNAMPT | |
| SCHEMBL4514525 | 0.87 | GPR119 (0.74) | GPR119TGFBR1 | |
| SCHEMBL4522460 | 0.87 | GPR119 (0.55) | GPR119TGFBR1LMNAMAPTALDH1A1 | |
| SCHEMBL4513931 | 0.86 | GPR119 (0.61) | GPR119TGFBR1LMNAMAPTALDH1A1 | |
| SCHEMBL4518131 | 0.86 | PTPN2 (0.62) | GPR119TGFBR1LMNAMAPTNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |