Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186 | 0.92 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL287 | 0.89 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL855 | 0.89 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL76 | 0.87 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL62 | 0.86 | AGTR1 (0.73) | AGTR1AGTR2 | |
| SCHEMBL7363748 | 0.86 | AGTR1 (0.61) | AGTR1AGTR2 | |
| Carboxylic Acid Metabolite SCHEMBL9327761 | 0.86 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL459 | 0.84 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL7171699 | 0.84 | AGTR1 (0.57) | AGTR1AGTR2 | |
| Olmesartan SCHEMBL29368106 | 0.84 | AGTR1 (0.73) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000067-A2 | TREATMENT OF CHRONIC RENAL FAILURE WITH IMIDAZOLE ANGIOTENSIN-II RECEPTOR ANTAGONISTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-09 | — | — | WO | disclosed |