Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354257 | 0.87 | TLR8 (0.54) | CYP2D6CYP2C19HRH4TLR8HRH3 | |
| SCHEMBL20434279 | 0.79 | TLR8 (0.73) | CYP2D6CYP2C19HRH4TLR8ALDH1A1 | |
| SCHEMBL10102121 | 0.78 | TLR8 (0.47) | CYP2D6CYP2C19HRH4TLR8MEN1 | |
| SCHEMBL12268319 | 0.77 | HRH4 (0.44) | CYP2D6CYP2C19HRH4TLR8HRH3 | |
| SCHEMBL25086774 | 0.77 | TLR8 (0.47) | CYP2D6CYP2C19HRH4TLR8HRH3 | |
| SCHEMBL30263108 | 0.77 | TLR8 (0.64) | CYP2D6CYP2C19HRH4TLR8 | |
| SCHEMBL29156884 | 0.77 | TLR8 (0.64) | CYP2D6CYP2C19HRH4TLR8 | |
| SCHEMBL25086837 | 0.77 | CYP2D6 (0.53) | CYP2D6CYP2C19HRH4TLR8HRH3 | |
| Bromide SCHEMBL30263107 | 0.75 | TLR8 (0.46) | CYP2D6CYP2C19HRH4TLR8HRH3 | |
| Bromide SCHEMBL30263110 | 0.75 | TLR8 (0.46) | CYP2D6CYP2C19HRH4TLR8HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578745-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |
| WO-1992017490-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1992-10-15 | — | — | WO | disclosed |