Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.76 |
| ▸ | F2 | P00734 | 16/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7463837 | 0.94 | F10 (0.67) | F10F2PRSS1ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7458805 | 0.86 | F10 (0.56) | F10F2PRSS1 | |
| Hydrochloric Acid SCHEMBL7361309 | 0.85 | F10 (0.98) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7451754 | 0.84 | F10 (0.70) | F10F2PRSS1 | |
| SCHEMBL7367187 | 0.82 | F10 (0.68) | F10F2PRSS1ITGB3ITGA2B | |
| SCHEMBL7365691 | 0.80 | F10 (0.86) | F10F2PRSS1 | |
| SCHEMBL7457516 | 0.78 | F10 (0.82) | F10F2PRSS1 | |
| SCHEMBL7363395 | 0.76 | F10 (0.83) | F10F2PRSS1 | |
| SCHEMBL7365365 | 0.76 | F10 (1.00) | F10F2PRSS1 | |
| SCHEMBL7454445 | 0.76 | F10 (1.00) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |