Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.83 |
| ▸ | F2 | P00734 | 14/20 | 0.83 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.83 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7458596 | 0.95 | F2 (0.75) | F10F2PRSS1TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL8345456 | 0.86 | F10 (0.90) | F10F2PRSS1 | |
| SCHEMBL7458603 | 0.86 | F10 (0.79) | F10F2PRSS1HDAC8 | |
| Hydrochloric Acid SCHEMBL7361309 | 0.82 | F10 (0.98) | F10F2PRSS1 | |
| SCHEMBL7363398 | 0.82 | F10 (0.58) | F10F2PRSS1HDAC8HTR6 | |
| SCHEMBL7365691 | 0.81 | F10 (0.86) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7451754 | 0.79 | F10 (0.70) | F10F2PRSS1TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL7458607 | 0.78 | F10 (0.53) | F10F2PRSS1HDAC8HTR6 | |
| SCHEMBL7367187 | 0.77 | F10 (0.68) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7454337 | 0.77 | F10 (0.74) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |