Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 6/20 | 0.69 |
| ▸ | MMP2 | P08253 | 12/20 | 0.53 |
| ▸ | MMP9 | P14780 | 3/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 13/20 | 0.50 |
| ▸ | MMP1 | P03956 | 11/20 | 0.50 |
| ▸ | MMP7 | P09237 | 9/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366820 | 1.00 | BIRC2 (0.69) | BIRC2MMP2MMP9MMP8MMP3 | |
| SCHEMBL7366830 | 1.00 | BIRC2 (0.69) | BIRC2MMP2MMP9MMP8MMP3 | |
| SCHEMBL7430975 | 0.83 | BIRC2 (0.68) | BIRC2MMP2MMP9MMP3MMP1 | |
| SCHEMBL7430956 | 0.83 | BIRC2 (0.68) | BIRC2MMP2MMP9MMP3MMP1 | |
| SCHEMBL7430963 | 0.83 | BIRC2 (0.68) | BIRC2MMP2MMP9MMP3MMP1 | |
| SCHEMBL7368616 | 0.82 | MMP1 (0.74) | BIRC2MMP2MMP9MMP8MMP3 | |
| SCHEMBL7368615 | 0.82 | MMP1 (0.74) | BIRC2MMP2MMP9MMP8MMP3 | |
| SCHEMBL7368611 | 0.82 | MMP1 (0.74) | BIRC2MMP2MMP9MMP8MMP3 | |
| SCHEMBL7368591 | 0.80 | BIRC2 (0.51) | BIRC2MMP2MMP9MMP8MMP3 | |
| SCHEMBL7368588 | 0.80 | BIRC2 (0.51) | BIRC2MMP2MMP9MMP8MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231081-B1 | HYDROXAMIC ACIDS | ICI AMERICAS INC. (US) | 1993-03-17 | — | — | EP | claimed |
| US-4771038-A | Hydroxamic acids | ICI AMERICAS INC. (US) | 1988-09-13 | — | — | US | claimed |
| EP-0231081-B1 | HYDROXAMIC ACIDS | ICI AMERICAS INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4771038-A | Hydroxamic acids | ICI AMERICAS INC. (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0231081-A2 | Hydroxamic acids | ICI AMERICAS INC. (US) | 1987-08-05 | — | — | EP | disclosed |