Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | POLB | P06746 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | BLM | P54132 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | APEX1 | P27695 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | HBB | P68871 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362351 | 0.89 | ATP1A1 (0.43) | MAPTPOLBKDM4EHPGDMEN1 | |
| SCHEMBL22966122 | 0.85 | SELL (0.33) | MAPTPOLBKDM4EHPGDMEN1 | |
| SCHEMBL24674099 | 0.74 | KDM4E (0.31) | MAPTPOLBKDM4EHPGDMEN1 | |
| SCHEMBL22063037 | 0.74 | KDM4E (0.31) | MAPTPOLBKDM4EHPGDMEN1 | |
| SCHEMBL7230275 | 0.68 | ATP1A1 (0.57) | MAPTPOLBKDM4EHPGDMEN1 | |
| SCHEMBL11416722 | 0.67 | KMT2A (0.45) | MAPTPOLBKDM4EHPGDMEN1 | |
| SCHEMBL22966139 | 0.65 | SELL (0.42) | MAPTPOLBKDM4EHPGDMEN1 | |
| SCHEMBL7361574 | 0.65 | ATP1A1 (0.39) | MAPTKDM4EHPGDMEN1GAA | |
| SCHEMBL22738311 | 0.60 | GAA (0.42) | MAPTPOLBKDM4EHPGDMEN1 | |
| SCHEMBL7227954 | 0.60 | ATP1A1 (0.79) | MAPTPOLBKDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888052-A4 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORP (US) | 2002-05-22 | — | — | EP | claimed |
| EP-0888052-A1 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORPORATION (US) | 1999-01-07 | — | — | EP | claimed |
| WO-1997034482-A1 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORP. (US) | 1997-09-25 | — | — | WO | claimed |
| US-5977077-A | PARASITICIDES; ANTIPROTOZOA AGENT | INTERLAB CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |