Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.41 |
| ▸ | YAP1 | P46937 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342434 | 0.95 | AVPR2 (0.42) | CCR8AVPR2AVPR1AAVPR1BYAP1 | |
| SCHEMBL7370102 | 0.92 | MEN1 (0.45) | CCR8ADRA1DADRA1AADRA1BPLK1 | |
| SCHEMBL7339114 | 0.91 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BADRA1DADRA1A | |
| SCHEMBL7339652 | 0.89 | AVPR2 (0.42) | CCR8AVPR2AVPR1AAVPR1BALDH1A1 | |
| SCHEMBL7781259 | 0.89 | NPC1 (0.42) | KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7778279 | 0.87 | AVPR2 (0.47) | AVPR2AVPR1AAVPR1BMAPTMEN1 | |
| SCHEMBL7338105 | 0.86 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BADRA1DADRA1A | |
| SCHEMBL7343158 | 0.86 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BMAPTTP53 | |
| SCHEMBL7336278 | 0.86 | AVPR2 (0.48) | AVPR2AVPR1AAVPR1BKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7336979 | 0.85 | AVPR2 (0.40) | CCR8AVPR2AVPR1AAVPR1BADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |