Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | F13A1 | P00488 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906876 | 0.95 | FFAR1 (0.56) | FFAR1MAPTRXFP1HDAC3HDAC4 | |
| SCHEMBL30740885 | 0.88 | FFAR1 (0.62) | FFAR1FFAR4 | |
| SCHEMBL447652 | 0.88 | FFAR1 (0.62) | FFAR1FFAR4 | |
| SCHEMBL28248440 | 0.84 | CYP19A1 (0.46) | FFAR1MAPTSMN1; SMN2 | |
| Phenyl Propionic Acid SCHEMBL5407020 | 0.82 | FFAR1 (0.68) | FFAR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22826566 | 0.82 | MAPT (0.67) | MAPTRXFP1F13A1HDAC3HDAC4 | |
| SCHEMBL7094632 | 0.81 | TSHR (0.52) | FFAR1 | |
| SCHEMBL29045424 | 0.81 | FFAR1 (0.46) | FFAR1MAPTSMN1; SMN2FFAR4 | |
| SCHEMBL28248935 | 0.80 | CYP19A1 (0.46) | FFAR1MAPTSMN1; SMN2 | |
| SCHEMBL6952816 | 0.79 | FFAR1 (0.46) | FFAR1SMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441974-A | Phenyl amidines lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-08-15 | — | — | US | disclosed |
| WO-1993012103-A1 | PHENYL AMIDINES LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-06-24 | — | — | WO | disclosed |