Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4837680 | 0.95 | TSHR (0.53) | TSHRHPGDALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL12255638 | 0.89 | TSHR (0.56) | TSHRHPGDALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL15266535 | 0.82 | TSHR (0.49) | TSHRHPGDALDH1A1CNR2FFAR1 | |
| SCHEMBL7367036 | 0.81 | FFAR1 (0.55) | FFAR1 | |
| SCHEMBL1558841 | 0.80 | ALDH1A1 (0.51) | TSHRHPGDALDH1A1FFAR1GAA | |
| SCHEMBL6002358 | 0.79 | TSHR (0.44) | TSHRHPGDALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL28248440 | 0.79 | CYP19A1 (0.46) | TSHRHPGDALDH1A1FFAR1 | |
| SCHEMBL6001767 | 0.79 | TSHR (0.44) | TSHRHPGDALDH1A1CNR2FFAR1 | |
| SCHEMBL13948679 | 0.78 | CYP4F2 (0.55) | TSHRHPGDALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL31155814 | 0.78 | CYP4F2 (0.55) | TSHRHPGDCYP4F2CYP4A11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064065-B1 | IMPROVED METHOD FOR ENRICHING OPTICAL ISOMERS BY MEANS OF SIMULATED MOBILE BED | NOVASEP S A (FR) | 2003-08-27 | — | — | EP | disclosed |
| US-6409923-B1 | CHIRAL CHROMATOGRAPHY, CHARGE INCREASE COMBINED WITH AN APPROPRIATE MODIFICATION OF THE DISCHARGE FLOW | NOVASEP S.A. (FR) | 2002-06-25 | — | — | US | disclosed |
| CN-1004351-B | Method for preparing selaginellin related compound with phenylene | 微生物化学研究会 | 1989-05-31 | — | — | CN | disclosed |
| EP-0153720-B1 | SPERGUALIN-RELATED COMPOUNDS HAVING A PHENYLENE GROUP, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1988-11-09 | — | — | EP | disclosed |
| CN-85101425-A | Have Si Baige Eyring allied compound of phenylene and preparation method thereof | — | 1987-01-17 | — | — | CN | disclosed |
| US-4556735-A | BACTERICIDE, ANTITUMOR AGENT | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYUKAI (JP) | 1985-12-03 | — | — | US | disclosed |
| EP-0153720-A2 | Spergualin-related compounds having a phenylene group, a process for their preparation and their use as medicaments | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1985-09-04 | — | — | EP | disclosed |