Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 7/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375472 | 0.86 | TUBB4A (0.47) | TEKTLR8TLR7TUBB4ATUBB | |
| SCHEMBL10564760 | 0.77 | TUBB4A (0.45) | TEKTLR8TLR7TUBB4ATUBB | |
| SCHEMBL7271721 | 0.77 | PDE5A (0.53) | TEKMAPK1SMN1; SMN2PDE5APDE3B | |
| SCHEMBL10518202 | 0.77 | PDE5A (0.65) | TEKSMN1; SMN2PDE5APDE3BPDE3A | |
| SCHEMBL7372679 | 0.77 | KDM4E (0.44) | TEKTUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL9838283 | 0.76 | PDE5A (0.53) | TEKMAPK1SMN1; SMN2PDE5APDE3B | |
| Hydrochloric Acid SCHEMBL7277930 | 0.76 | PDE5A (0.53) | TEKMAPK1SMN1; SMN2PDE5APDE3B | |
| SCHEMBL7377111 | 0.73 | NPY5R (0.54) | TEKTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20445308 | 0.73 | PDE2A (0.55) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL11774181 | 0.72 | PDE2A (0.72) | PDE5APDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |