SCHEMBL7367142

SCHEMBL7367142

C[C@H]1CN(Cc2ccc3c(N)ncnc3c2)CCN1Cc1cc2ccc(Cl)cc2s1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
F10 P00742 13/20 0.56
ACHE P22303 1/20 0.35
BACE1 P56817 1/20 0.35
HTT P42858 1/20 0.35
OGA O60502 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
DRD2 P14416 1/20 0.35
DRD4 P21917 1/20 0.35
CCR1 P32246 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7374382 0.94 F10 (0.51) F10ACHEBACE1HTTOGA
SCHEMBL7377711 0.94 F10 (0.51) F10ACHEBACE1HTTOGA
SCHEMBL7372583 0.86 F10 (0.53) F10
SCHEMBL27551214 0.85 F10 (0.55) F10ACHEBACE1HTT
SCHEMBL4388720 0.84 F10 (0.61) F10
SCHEMBL4388718 0.84 F10 (0.61) F10
SCHEMBL4397262 0.84 F10 (0.61) F10
SCHEMBL27592058 0.83 F10 (0.51) F10
SCHEMBL27591519 0.83 F10 (0.51) F10
SCHEMBL7374255 0.82 F10 (0.70) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051176-A4 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARM PROD INC (US) 2002-06-12 EP disclosed
EP-1051176-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS Aventis Pharmaceuticals Products Inc. (US) 2000-11-15 EP disclosed
WO-1999037304-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-07-29 WO disclosed