SCHEMBL7374255

SCHEMBL7374255

C[C@H]1CN(Cc2ccc3c(N)ncnc3c2)CCN1S(=O)(=O)c1cc2ccc(Cl)cc2s1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 17/20 0.70
PTGDR2 Q9Y5Y4 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1651748 0.85 F10 (0.74) F10
SCHEMBL4390968 0.85 F10 (0.74) F10
SCHEMBL27551230 0.83 F10 (0.60) F10
SCHEMBL7371705 0.83 F10 (0.56) F10PTGDR2
SCHEMBL7410804 0.83 F10 (0.48) F10PTGDR2
SCHEMBL4393927 0.82 F10 (0.72) F10
SCHEMBL1651698 0.82 F10 (0.72) F10
SCHEMBL7367142 0.82 F10 (0.56) F10
SCHEMBL4388199 0.81 F10 (0.66) F10
SCHEMBL1386592 0.81 F10 (0.80) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051176-A4 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARM PROD INC (US) 2002-06-12 EP disclosed
EP-1051176-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS Aventis Pharmaceuticals Products Inc. (US) 2000-11-15 EP disclosed
WO-1999037304-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-07-29 WO disclosed