Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 6/20 | 0.65 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.65 |
| ▸ | HTR3B | O95264 | 4/20 | 0.65 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.65 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.65 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | HTR5A | P47898 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290995 | 0.88 | HTR3A (0.55) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL15695607 | 0.85 | CHRNA7 (0.62) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL10342300 | 0.85 | CHRNA7 (0.74) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL10436323 | 0.85 | CHRNA7 (0.74) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL7278547 | 0.83 | CHRNA7 (0.72) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL7291446 | 0.83 | CHRNA7 (0.72) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL9601320 | 0.83 | CHRNA7 (0.72) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Pnu-282987 SCHEMBL10436185 | 0.79 | CHRNA7 (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL15695579 | 0.79 | CHRNA7 (0.62) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Pnu-282987 SCHEMBL6208420 | 0.79 | CHRNA7 (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563087-A1 | AZABICYCLIC AMIDES OR ESTERS OF HALOGENATED BENZOIC ACIDS | BEECHAM GROUP PLC (GB) | 1993-10-06 | — | — | EP | claimed |
| WO-1992011259-A1 | AZABICYCLIC AMIDES OR ESTERS OF HALOGENATED BENZOIC ACIDS | BEECHAM GROUP PLC (GB) | 1992-07-09 | — | — | WO | claimed |