Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.61 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360128 | 0.92 | F2 (0.69) | F2MGLLSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7364521 | 0.82 | F2 (0.86) | F2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7359608 | 0.80 | F2 (0.68) | F2MGLLALDH1A1KMT2AMEN1 | |
| SCHEMBL8029555 | 0.77 | F2 (0.53) | F2MGLLSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7367913 | 0.76 | F2 (1.00) | F2MGLLSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7367339 | 0.74 | GRIN2B (0.53) | MGLLLMNA | |
| SCHEMBL7359275 | 0.73 | F2 (0.74) | F2MGLLSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7359272 | 0.73 | F2 (0.74) | F2MGLLSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL19848516 | 0.73 | CYP11B1 (0.60) | SMN1; SMN2LMNAALDH1A1HTT | |
| SCHEMBL8035205 | 0.72 | F2 (0.62) | F2MGLLSMN1; SMN2ALDH1A1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043257-A | ANTICOAGULANT; PYRIDINE SUBSTITUTED INDAZOLE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0960102-A1 | AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN | Du Pont Pharmaceuticals Company (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5886191-A | ANTICOAGULANTS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| WO-1998001428-A1 | AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-01-15 | — | — | WO | disclosed |