Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.62 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CCR3 | P51677 | 3/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434637 | 0.85 | F2 (0.85) | F2PRSS1ALDH1A1TACR1 | |
| SCHEMBL8029555 | 0.82 | F2 (0.53) | F2PRSS1MGLLALDH1A1SMN1; SMN2 | |
| SCHEMBL7359275 | 0.82 | F2 (0.74) | F2PRSS1MGLLALDH1A1SMN1; SMN2 | |
| SCHEMBL7359272 | 0.82 | F2 (0.74) | F2PRSS1MGLLALDH1A1SMN1; SMN2 | |
| SCHEMBL7359608 | 0.75 | F2 (0.68) | F2PRSS1MGLLALDH1A1CCR3 | |
| SCHEMBL7360128 | 0.74 | F2 (0.69) | F2PRSS1MGLLALDH1A1SMN1; SMN2 | |
| SCHEMBL7367336 | 0.72 | F2 (0.61) | F2MGLLALDH1A1SMN1; SMN2CCR3 | |
| SCHEMBL8031092 | 0.70 | F2 (1.00) | F2PRSS1 | |
| SCHEMBL8029375 | 0.67 | F2 (0.70) | F2MGLLALDH1A1CCR3 | |
| SCHEMBL27484312 | 0.67 | ALDH1A1 (0.54) | F2PRSS1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043257-A | ANTICOAGULANT; PYRIDINE SUBSTITUTED INDAZOLE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| US-5886191-A | ANTICOAGULANTS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-03-23 | — | — | US | disclosed |