Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831591 | 0.89 | NPC1 (0.45) | NPC1ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL20474086 | 0.86 | NPC1 (0.46) | NPC1ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL1287150 | 0.86 | NPC1 (0.46) | NPC1ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL6675373 | 0.86 | NPC1 (0.46) | NPC1ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL7364105 | 0.85 | NPC1 (0.51) | NPC1ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL5523207 | 0.85 | CTSS (0.50) | — | |
| SCHEMBL6830751 | 0.84 | KMT2A (0.43) | NPC1ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL23728158 | 0.84 | NPC1 (0.67) | NPC1ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL31234426 | 0.84 | NPC1 (0.67) | NPC1ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL27668003 | 0.84 | NPC1 (0.67) | NPC1ADRB2ADRB1ADRB3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |