Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 10/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368037 | 0.94 | HPGD (0.51) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL7367092 | 0.86 | NR1H4 (0.46) | NR1H4PPARGPPARA | |
| SCHEMBL7370555 | 0.86 | NR1H4 (0.59) | SMN1; SMN2RXFP1NR1H4PPARGPPARA | |
| SCHEMBL7366501 | 0.84 | F10 (0.47) | ALDH1A1HPGDNR1H4MAPK1PPARG | |
| SCHEMBL7372132 | 0.82 | NR1H4 (0.43) | RAB9AMEN1KMT2AALDH1A1HTT | |
| SCHEMBL7365886 | 0.82 | RAB9A (0.47) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL6172966 | 0.82 | NR1H4 (0.46) | MAPTMEN1KMT2ASMN1; SMN2NR1H4 | |
| SCHEMBL6177517 | 0.82 | MAPT (0.42) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL6170045 | 0.82 | ESR1 (0.54) | RAB9AMAPTMEN1KMT2ANPC1 | |
| SCHEMBL6171764 | 0.80 | RAB9A (0.53) | RAB9AMAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1019045-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |