Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 15/20 | 0.62 |
| ▸ | MMP3 | P08254 | 10/20 | 0.62 |
| ▸ | MMP9 | P14780 | 5/20 | 0.62 |
| ▸ | MMP1 | P03956 | 4/20 | 0.62 |
| ▸ | MMP14 | P50281 | 2/20 | 0.62 |
| ▸ | ADAM10 | O14672 | 13/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433723 | 0.88 | MMP2 (0.64) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6968340 | 0.84 | MMP2 (0.63) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6964678 | 0.83 | MMP2 (0.67) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6433718 | 0.83 | MMP2 (0.62) | MMP2MMP3MMP9MMP1MMP14 | |
| Hydrochloric Acid SCHEMBL6965337 | 0.83 | MMP2 (0.66) | MMP2MMP3MMP9MMP1MMP14 | |
| Hydrochloric Acid SCHEMBL6437678 | 0.83 | MMP2 (0.62) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6971907 | 0.82 | MMP2 (0.65) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6433286 | 0.81 | MMP2 (0.64) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6435723 | 0.79 | MMP2 (0.84) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6436456 | 0.78 | MMP2 (0.63) | MMP2MMP3MMP9MMP1MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |