Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.58 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368644 | 0.83 | CTSS (0.60) | CTSS | |
| SCHEMBL7788068 | 0.79 | CTSS (0.60) | CTSSCTSLCTSK | |
| SCHEMBL5758383 | 0.77 | CTSS (0.62) | CTSS | |
| SCHEMBL5758653 | 0.77 | CTSS (0.53) | CTSSCTSLCTSK | |
| SCHEMBL5758689 | 0.76 | CTSS (0.58) | CTSSCTSLCTSK | |
| SCHEMBL5758712 | 0.74 | CTSS (0.69) | CTSS | |
| SCHEMBL3023686 | 0.74 | CTSS (1.00) | CTSSCTSLCTSK | |
| SCHEMBL3023690 | 0.74 | CTSS (1.00) | CTSSCTSLCTSK | |
| SCHEMBL4450101 | 0.73 | CTSS (0.61) | CTSS | |
| SCHEMBL4450104 | 0.73 | CTSS (0.61) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204652-A1 | NOVEL SUCCINATE DERIVATIVE COMPOUNDS USEFUL AS CYSTEINE PROTEASE INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009110-A1 | NOVEL SUCCINATE DERIVATIVE COMPOUNDS USEFUL AS CYSTEINE PROTEASE INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-02-08 | — | — | WO | disclosed |