Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 10/20 | 0.51 |
| ▸ | PLG | P00747 | 5/20 | 0.51 |
| ▸ | PLAT | P00750 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7365698 | 0.99 | PLAU (0.50) | PLAUPLGPLATTHRBNLRP3 | |
| Hydrochloric Acid SCHEMBL7372717 | 0.93 | PLAU (0.43) | PLAUPLGPLATTHRBNLRP3 | |
| Hydrochloric Acid SCHEMBL7363441 | 0.85 | PLAU (0.53) | PLAUPLGPLATCYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL7376139 | 0.82 | PLAU (0.51) | PLAUPLGPLATALDH1A1 | |
| SCHEMBL7371811 | 0.81 | PLAU (0.41) | PLAUPLGPLATKDM4ECYP1A2 | |
| SCHEMBL7050306 | 0.81 | PLAU (0.37) | PLAUPLGPLATKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7588559 | 0.81 | PLG (0.52) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL7379850 | 0.80 | PLAU (0.40) | PLAUPLGPLATKDM4ECYP1A2 | |
| SCHEMBL7366260 | 0.80 | PLAU (0.39) | PLAUPLGPLATKDM4EMEN1 | |
| SCHEMBL7374993 | 0.80 | PLAU (0.42) | PLAUPLGPLATKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |