Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365265 | 0.84 | MAPT (0.39) | MMP8PIN1CYP3A4MEN1KMT2A | |
| SCHEMBL12226103 | 0.80 | TDP1 (0.48) | MMP8PIN1NPC1TSHRLMNA | |
| SCHEMBL12226100 | 0.79 | MMP8 (0.43) | MMP8PIN1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16291475 | 0.78 | MMP8 (0.42) | MMP8PIN1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1774142 | 0.72 | PPARA (0.50) | SMN1; SMN2MEN1KMT2AATMALDH1A1 | |
| SCHEMBL9989812 | 0.72 | PPARA (0.50) | SMN1; SMN2MEN1KMT2AATMALDH1A1 | |
| SCHEMBL9990116 | 0.71 | CHRM3 (0.42) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9990118 | 0.71 | CHRM3 (0.42) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9300028 | 0.71 | CYP3A4 (0.39) | SMN1; SMN2CYP3A4ALDH1A1TSHRCASP1 | |
| SCHEMBL9299497 | 0.71 | CYP3A4 (0.39) | SMN1; SMN2CYP3A4ALDH1A1TSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014706-A1 | CYCLOPENTANE-DERIVED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS | PFIZER LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |