Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KYNU | Q16719 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9424317 | 0.81 | TSHR (0.53) | MEN1KMT2APTPN1NPC1RAB9A | |
| SCHEMBL9155285 | 0.79 | CA12 (0.55) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL9155282 | 0.78 | CA12 (0.56) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL6538869 | 0.74 | MEN1 (0.63) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL15720647 | 0.74 | CA12 (0.63) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL20997315 | 0.74 | CA12 (0.49) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL28537302 | 0.74 | CA12 (0.55) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL22468533 | 0.74 | MEN1 (0.66) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL1949474 | 0.74 | CA12 (0.55) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL22966170 | 0.73 | CA12 (0.58) | MEN1KMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997011960-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | JAPAT LTD. (CH) | 1997-04-03 | — | — | WO | disclosed |