Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 1/20 | 0.60 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364463 | 0.85 | BCHE (0.67) | SLC6A12SLC6A13EPHX2RAB9ANPC1 | |
| SCHEMBL5364553 | 0.83 | DRD4 (0.65) | HPGDEPHX2ALDH1A1DRD4 | |
| SCHEMBL13538758 | 0.83 | DRD4 (0.57) | HPGDEPHX2ALDH1A1DRD4 | |
| SCHEMBL3028796 | 0.82 | BCHE (0.58) | SLC6A12SLC6A13EPHX2RAB9ANPC1 | |
| SCHEMBL7374112 | 0.82 | EPHX2 (0.50) | SLC6A12SLC6A13EPHX2ALDH1A1DRD4 | |
| SCHEMBL3026490 | 0.81 | HDAC4 (0.60) | EPHX2ALDH1A1DRD4 | |
| SCHEMBL2424663 | 0.80 | RAB9A (0.65) | HPGDEPHX2RAB9ACHRM3MCHR1 | |
| SCHEMBL2769124 | 0.80 | DRD4 (0.61) | EPHX2ALDH1A1DRD4 | |
| SCHEMBL2770194 | 0.80 | DRD4 (0.61) | EPHX2ALDH1A1DRD4 | |
| SCHEMBL5429645 | 0.80 | DRD4 (0.61) | EPHX2ALDH1A1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243959-B1 | SUBSTITUTED BENZAMIDE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1992-08-19 | — | — | EP | disclosed |
| US-4870074-A | Substituted benzamide derivatives, for enhancing gastrointestinal motility | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0243959-A1 | Substituted benzamide derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-11-04 | — | — | EP | disclosed |