Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125912 | 0.94 | MTNR1B (0.54) | MTNR1BMEN1KMT2AESR1ESR2 | |
| SCHEMBL8125915 | 0.94 | MTNR1B (0.54) | MTNR1BMEN1KMT2AESR1ESR2 | |
| SCHEMBL8125910 | 0.94 | MTNR1B (0.54) | MTNR1BMEN1KMT2AESR1ESR2 | |
| SCHEMBL14959567 | 0.78 | MTNR1B (0.52) | MTNR1BMEN1KMT2AOPRD1ACE | |
| SCHEMBL8125615 | 0.77 | MTNR1B (0.47) | MTNR1BMEN1KMT2AESR1ESR2 | |
| SCHEMBL7435382 | 0.77 | MTNR1B (0.47) | MTNR1BMEN1KMT2AESR1ESR2 | |
| SCHEMBL7435390 | 0.77 | MTNR1B (0.47) | MTNR1BMEN1KMT2AESR1ESR2 | |
| SCHEMBL11929926 | 0.76 | MTNR1B (0.47) | MTNR1BMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL12187751 | 0.76 | MTNR1B (0.49) | MTNR1BMEN1KMT2AOPRD1NPSR1 | |
| SCHEMBL30878595 | 0.75 | DRD1 (0.55) | MTNR1BESR1ESR2ACENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822934-A1 | ANTITHROMBOTIC AMIDINOTETRAHYDROPYRIDYLALANINE DERIVATIVES | Pfizer Research and Development Company, N.V./S.A. (IE) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996033993-A1 | ANTITHROMBOTIC AMIDINOTETRAHYDROPYRIDYLALANINE DERIVATIVES | PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. (IE) | 1996-10-31 | — | — | WO | disclosed |