Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | OXTR | P30559 | 2/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3503762 | 1.00 | MAOB (0.49) | MAOBNOTUMPPARDPPARAOXTR | |
| SCHEMBL3505122 | 0.84 | QPCT (0.36) | NOTUMPPARDPPARAOXTRQPCT | |
| SCHEMBL7372353 | 0.84 | QPCT (0.36) | NOTUMPPARDPPARAOXTRQPCT | |
| SCHEMBL7372356 | 0.84 | QPCT (0.36) | NOTUMPPARDPPARAOXTRQPCT | |
| SCHEMBL7340025 | 0.79 | MAOB (0.47) | MAOBPPARDPPARAMGAT2KCNE1 | |
| SCHEMBL7340022 | 0.79 | MAOB (0.47) | MAOBPPARDPPARAMGAT2KCNE1 | |
| SCHEMBL7342239 | 0.78 | HTR2C (0.49) | NOTUMOXTR | |
| SCHEMBL8742792 | 0.78 | HTR2C (0.49) | NOTUMOXTR | |
| SCHEMBL7366736 | 0.78 | HTR2C (0.49) | NOTUMOXTR | |
| SCHEMBL7343392 | 0.77 | MAOB (0.45) | MAOBPPARDPPARAMGAT2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699680-B1 | Oxazoloquinolinone derivatives, their preparation and their use in therapy | SANOFI SYNTHELABO (FR) | 2000-03-08 | — | — | EP | disclosed |
| US-5641785-A | ANTIDEPRESSANTS, NERVOUS SYSTEM DISORDERS | SYNTHELABO (FR) | 1997-06-24 | — | — | US | disclosed |
| EP-0699680-A1 | Oxazoloquinolinone derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1996-03-06 | — | — | EP | disclosed |