Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.56 |
| ▸ | ACE | P12821 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CPA3 | P15088 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367991 | 0.99 | MME (0.57) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL2680002 | 0.86 | CPA3 (0.55) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL7366168 | 0.81 | CYP1A2 (0.54) | MMEACEHPGD | |
| SCHEMBL7377128 | 0.79 | CYP1A2 (0.55) | MMEACE | |
| SCHEMBL27533361 | 0.78 | HTT (0.48) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL3266606 | 0.78 | HTT (0.48) | ALDH1A1 | |
| SCHEMBL3267717 | 0.78 | HTT (0.48) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL9396607 | 0.76 | CPA3 (0.43) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL10800303 | 0.75 | TDP1 (0.61) | MMEACEALDH1A1HPGDMAPK1 | |
| Benzene SCHEMBL7371236 | 0.73 | HTT (0.44) | ACEHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280627-B1 | DERIVATIVES OF N-SUBSTITUTED ALPHA-MERCAPTOMETHYL-BENZENE-PROPANAMIDE, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-04-21 | — | — | EP | disclosed |
| US-4839358-A | ANALGESICS, ANTIDEPRESSANTS, ANTIANXIETY AGENTS | ROUSSEL UCLAF (FR) | 1989-06-13 | — | — | US | disclosed |
| EP-0280627-A2 | Derivatives of N-substituted alpha-mercaptomethyl-benzene-propanamide, process for their preparation, their use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1988-08-31 | — | — | EP | disclosed |