Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.41 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28148216 | 0.89 | HSD11B1 (0.34) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30510464 | 0.88 | — | — | |
| SCHEMBL1046456 | 0.82 | HSD11B1 (0.42) | HSD11B1CA2CA1HSD11B2 | |
| SCHEMBL1223355 | 0.82 | HSD11B1 (0.36) | LMNAHSD11B1ALDH1A1HSD11B2 | |
| SCHEMBL1046838 | 0.80 | EPHX2 (0.46) | TSHRHSD11B1CA2CA1CA12 | |
| SCHEMBL28067766 | 0.77 | HSD11B1 (0.39) | HSD11B1HSD11B2 | |
| Ethylene SCHEMBL1043237 | 0.77 | EPHX2 (0.43) | TSHRHSD11B1CA2CA1CA12 | |
| SCHEMBL28375490 | 0.77 | GAA (0.42) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8796120 | 0.74 | — | — | |
| SCHEMBL36264 | 0.72 | GAA (0.44) | LMNAGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640081-A | Adamantane sulfonamide compound as well as preparation method and application thereof | 重庆医科大学 | 2023-08-25 | — | — | CN | claimed |
| CN-106432025-B | Adamantane sulfonamide compound and preparation and application thereof | 重庆医科大学 | 2023-06-09 | — | — | CN | claimed |
| CN-116640081-A | Adamantane sulfonamide compound as well as preparation method and application thereof | 重庆医科大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-116640081-A | Adamantane sulfonamide compound as well as preparation method and application thereof | 重庆医科大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-116640081-A | Adamantane sulfonamide compound as well as preparation method and application thereof | 重庆医科大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-106432025-B | Adamantane sulfonamide compound and preparation and application thereof | 重庆医科大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-106432025-B | Adamantane sulfonamide compound and preparation and application thereof | 重庆医科大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-106432025-B | Adamantane sulfonamide compound and preparation and application thereof | 重庆医科大学 | 2023-06-09 | — | — | CN | disclosed |
| US-10649329-B2 | Active light sensitive or radiation sensitive resin composition, active light sensitive or radiation sensitive film, pattern forming method, method for manufacturing electronic device, and electronic device | FUJIFILM CORPORATION (JP) | 2020-05-12 | — | — | US | disclosed |
| US-20170097565-A1 | ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE RESIN COMPOSITION, ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE FILM, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE | FUJIFILM CORPORATION (JP) | 2017-04-06 | — | — | US | disclosed |
| US-20170097565-A1 | ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE RESIN COMPOSITION, ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE FILM, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE | FUJIFILM CORPORATION (JP) | 2017-04-06 | — | — | US | disclosed |
| US-5726158-A | INHIBITORS OF HUMAN LEUKOCYTE ELASTASE USEFUL IN TREATING TISSUE DEGENERATIVE DISEASES; TRIFLUOROMETHYL KETONE SUBSTITUTED DI-, TRI-, AND TETRA-PEPTIDE DERIVATIVES | ZENECA INC. (US) | 1998-03-10 | — | — | US | disclosed |
| US-5414132-A | Peptide intermediates | ZENECA INC. (US) | 1995-05-09 | — | — | US | disclosed |
| CN-1027640-C | Process for producing novel trifluoromethyl ketone substituted peptide derivatives | ICI AMERICA INC (US) | 1995-02-15 | — | — | CN | disclosed |
| US-5194588-A | Inhibitors of human leukocyte elastase, di-, tri- and tetra-peptides | ICI AMERICAS INC. (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0189305-B1 | PEPTIDE DERIVATIVES | ICI AMERICAS INC. (US) | 1992-07-29 | — | — | EP | disclosed |
| US-5055450-A | Di-, tri- and tetrapeptides as inhibitors of human leukocyte elastase | ICI AMERICAS INC. (US) | 1991-10-08 | — | — | US | disclosed |
| US-4910190-A | Containing a nitrogen containing heterocycle ring structure | ICI AMERICAS INC. (US) | 1990-03-20 | — | — | US | disclosed |
| CN-86101066-A | Process for producing novel trifluoromethyl ketone substituted peptide derivatives | — | 1986-11-05 | — | — | CN | disclosed |
| EP-0189305-A2 | Peptide derivatives | ICI AMERICAS INC. (US) | 1986-07-30 | — | — | EP | disclosed |