Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 6/20 | 0.50 |
| ▸ | METAP2 | P50579 | 5/20 | 0.39 |
| ▸ | METAP1 | P53582 | 4/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369089 | 1.00 | REN (0.50) | RENMETAP2METAP1CTSKALDH1A1 | |
| SCHEMBL7327540 | 0.81 | REN (0.53) | RENMETAP2METAP1CTSKALDH1A1 | |
| SCHEMBL8682141 | 0.79 | REN (0.55) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL7279876 | 0.79 | REN (0.55) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL8682444 | 0.79 | REN (0.55) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL7301121 | 0.77 | REN (0.50) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL9260290 | 0.77 | REN (0.50) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL7317656 | 0.77 | REN (0.53) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL7291539 | 0.77 | REN (0.53) | RENMETAP2METAP1 | |
| SCHEMBL7317650 | 0.77 | REN (0.53) | RENMETAP2METAP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578745-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-01-19 | — | — | EP | claimed |
| WO-1992017490-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1992-10-15 | — | — | WO | claimed |