Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369578 | 1.00 | CYP2D6 (0.52) | CYP2D6CYP1A2CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL21449757 | 0.90 | CYP2D6 (0.49) | CYP2D6CYP1A2CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL70792 | 0.89 | CYP2D6 (0.55) | CYP2D6CYP1A2CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL8909581 | 0.84 | CA2 (0.40) | CYP2D6CYP1A2ALDH1A1KMT2ATSHR | |
| SCHEMBL6198029 | 0.82 | CYP2D6 (0.63) | CYP2D6CYP1A2CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL6198035 | 0.82 | CYP2D6 (0.63) | CYP2D6CYP1A2CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL2670048 | 0.82 | CYP2D6 (0.63) | CYP2D6CYP1A2CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL777214 | 0.82 | CYP2D6 (0.63) | CYP2D6CYP1A2CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL657896 | 0.81 | CYP2D6 (0.67) | CYP2D6CYP1A2CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL10376015 | 0.81 | CYP2D6 (0.67) | CYP2D6CYP1A2CYP3A4ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |