Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328042 | 0.87 | ACE (0.57) | ACEPTPN1MMEL3MBTL1NPSR1 | |
| SCHEMBL7289252 | 0.83 | PTPN1 (0.56) | ACEPTPN1MMEL3MBTL1LMNA | |
| SCHEMBL29814575 | 0.83 | ACE (0.53) | ACEPTPN1MMEL3MBTL1NPSR1 | |
| SCHEMBL7290358 | 0.82 | MME (0.54) | ACEMMEKMT2A | |
| SCHEMBL27521411 | 0.80 | ACE (0.63) | ACEMMEL3MBTL1NPSR1ECE1 | |
| SCHEMBL3818234 | 0.80 | ACE (0.63) | ACEMMEL3MBTL1NPSR1ECE1 | |
| SCHEMBL12205303 | 0.80 | ACE (0.50) | ACEPTPN1MMEL3MBTL1NPSR1 | |
| SCHEMBL22457558 | 0.80 | ACE (0.53) | ACEPTPN1MMEL3MBTL1NPSR1 | |
| SCHEMBL7373769 | 0.79 | ACE (0.74) | ACEMMEL3MBTL1NPSR1ECE1 | |
| SCHEMBL10030547 | 0.79 | ACE (0.74) | ACEMMEL3MBTL1NPSR1ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001973-A1 | COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999006433-A1 | COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | claimed |