Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30166173 | 0.77 | GAA (0.43) | EGFRIDO1RECQLEPHX2ATM | |
| SCHEMBL25180854 | 0.77 | GAA (0.43) | EGFRIDO1RECQLEPHX2ATM | |
| SCHEMBL25180855 | 0.77 | GAA (0.43) | EGFRIDO1RECQLEPHX2ATM | |
| SCHEMBL25180856 | 0.77 | GAA (0.43) | EGFRIDO1RECQLEPHX2ATM | |
| SCHEMBL3759735 | 0.72 | EGFR (0.48) | EGFRIDO1HSPA1APTPN7TDP1 | |
| SCHEMBL14077949 | 0.69 | MEN1 (0.43) | IDO1CYP2C19MEN1KMT2A | |
| SCHEMBL6409284 | 0.68 | IDO1 (0.41) | EGFRIDO1RECQLEPHX2ATM | |
| SCHEMBL691998 | 0.68 | MAPT (0.55) | IDO1TDP1MEN1KMT2A | |
| SCHEMBL13611951 | 0.68 | TDP1 (0.37) | EGFRIDO1HSPA1APTPN7TDP1 | |
| SCHEMBL4881527 | 0.67 | PTPRA (0.36) | IDO1RECQLEPHX2CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946542-A1 | INDANE OR DIHYDROINDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028293-A1 | INDANE OR DIHYDROINDOLE DERIVATIVES | H.LUNDBECK A/S (DK) | 1998-07-02 | — | — | WO | disclosed |