Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 7/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.39 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.39 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 5/20 | 0.39 |
| ▸ | CDK8 | P49336 | 5/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749486 | 0.92 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL8812468 | 0.91 | AVPR2 (0.37) | AVPR2AVPR1ACCNCCDK8RECQL | |
| SCHEMBL7373648 | 0.90 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BRECQL | |
| SCHEMBL7378099 | 0.87 | L3MBTL1 (0.43) | RECQL | |
| SCHEMBL7371623 | 0.87 | AVPR2 (0.45) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7371692 | 0.86 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7751053 | 0.86 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7372942 | 0.86 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7372097 | 0.85 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7377335 | 0.84 | AVPR2 (0.47) | AVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |