Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | LTK | P29376 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2145154 | 0.72 | MEN1 (0.47) | DYRK1AADORA2AIDO1 | |
| SCHEMBL7158075 | 0.71 | CYP2A6 (0.41) | MAP4K4IRAK4CHUKLIMK1MAP3K14 | |
| SCHEMBL3507599 | 0.68 | ESR1 (0.40) | MAP4K4LIMK1IDO1CYP2A6 | |
| SCHEMBL30536133 | 0.68 | ESR1 (0.40) | MAP4K4LIMK1IDO1CYP2A6 | |
| SCHEMBL5884603 | 0.68 | ADORA2A (0.50) | MAP4K4ADORA2A | |
| SCHEMBL3582506 | 0.68 | NR4A2 (0.56) | MAP4K4IRAK4CDK8DAPK3PRKACA | |
| SCHEMBL17660499 | 0.68 | MAP4K4 (0.77) | MAP4K4IRAK4CDK8CCNCCDKN1A | |
| SCHEMBL1420076 | 0.67 | KCNJ1 (0.53) | MAP4K4APPCSNK1A1PIN1CYP2A6 | |
| Hydrochloric Acid SCHEMBL3577659 | 0.67 | NR4A2 (0.54) | MAP4K4IRAK4CDK8DAPK3PRKACA | |
| SCHEMBL18658788 | 0.67 | MAP4K4 (0.45) | MAP4K4APPIRAK4CHUKCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049404-A1 | ANTICOAGULANT AGENTS | ELI LILLY AND COMPANY (US) | 1997-12-31 | — | — | WO | disclosed |