Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370934 | 0.92 | F2 (1.00) | F2PRSS1 | |
| SCHEMBL7363810 | 0.88 | F2 (0.78) | F2PRSS1 | |
| SCHEMBL7369356 | 0.87 | F2 (1.00) | F2PRSS1 | |
| SCHEMBL7364614 | 0.81 | F2 (0.68) | F2 | |
| SCHEMBL7715115 | 0.77 | F2 (0.65) | F2 | |
| SCHEMBL7718502 | 0.77 | F2 (0.86) | F2PRSS1 | |
| Hydrochloric Acid SCHEMBL7447792 | 0.77 | PRSS1 (0.89) | F2PRSS1 | |
| SCHEMBL7361368 | 0.75 | F2 (0.86) | F2PRSS1 | |
| SCHEMBL7369034 | 0.73 | F2 (0.60) | F2 | |
| SCHEMBL5854816 | 0.72 | F2 (0.87) | F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259506-A1 | PYRAZINONE THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 2002-11-27 | — | — | EP | disclosed |
| US-6387911-B1 | Pyrazinone thrombin inhibitors | MERCK & CO., INC. | 2002-05-14 | — | — | US | disclosed |
| WO-2001038323-A1 | PYRAZINONE THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2001-05-31 | — | — | WO | disclosed |