Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369034 | 0.89 | F2 (0.60) | F2 | |
| SCHEMBL7364614 | 0.86 | F2 (0.68) | F2 | |
| SCHEMBL5855403 | 0.82 | F2 (0.71) | F2 | |
| SCHEMBL7364554 | 0.82 | F2 (0.57) | F2 | |
| SCHEMBL7370934 | 0.79 | F2 (1.00) | F2 | |
| SCHEMBL7363810 | 0.77 | F2 (0.78) | F2 | |
| SCHEMBL7369397 | 0.77 | F2 (1.00) | F2 | |
| SCHEMBL23460612 | 0.76 | LMNA (0.41) | F2KDM4EALDH1A1 | |
| SCHEMBL23460733 | 0.75 | F2 (0.39) | F2KDM4EALDH1A1 | |
| SCHEMBL23460615 | 0.74 | F2 (0.61) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387911-B1 | Pyrazinone thrombin inhibitors | MERCK & CO., INC. | 2002-05-14 | — | — | US | disclosed |