SCHEMBL7369526

SCHEMBL7369526

CC(C)(C)OC(=O)c1cc2ccc(NC(=O)c3ccc(NS(C)(=O)=O)cc3NC(=O)C3CCN(c4ccncc4)CC3)cc2[nH]1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
F10 P00742 12/20 0.41
JAK2 O60674 3/20 0.39
HDAC1 Q13547 3/20 0.39
FGFR1 P11362 1/20 0.36
FGFR2 P21802 1/20 0.36
FGFR3 P22607 1/20 0.36
F2 P00734 2/20 0.36
ELANE P08246 1/20 0.36
KIF18A Q8NI77 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7372754 0.95 F10 (0.42) F10JAK2HDAC1F2ELANE
SCHEMBL7372221 0.92 F10 (0.39) F10F2ELANE
SCHEMBL7369776 0.89 F10 (0.36) F10FGFR1FGFR2FGFR3KIF18A
SCHEMBL6168826 0.89 RXFP2 (0.46) F10F2ELANE
SCHEMBL7374706 0.87 F10 (0.46) F10
SCHEMBL7369945 0.86 F10 (0.44) F10F2ELANE
SCHEMBL7374728 0.85 KIF18A (0.34) F10FGFR1FGFR2FGFR3KIF18A
SCHEMBL6170090 0.84 F10 (0.41) F10JAK2HDAC1F2ELANE
SCHEMBL6169978 0.84 RXFP2 (0.51) F10JAK2HDAC1F2
SCHEMBL6170463 0.79 RXFP2 (0.52) F10JAK2HDAC1F2ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999000128-A9 ANTITHROMBOTIC AGENTS LILLY CO ELI (US) 1999-08-05 WO disclosed