Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369923 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL73762 | 0.84 | MAPT (0.60) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL2121537 | 0.84 | MAPT (0.60) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL28205062 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL5870000 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL6374257 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL7130634 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL839404 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL3451868 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL31229238 | 0.78 | FOLH1 (0.48) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117841-A | USED TO TREAT STROKE, CEREBRAL ISCHEMIA, PAIN, HEAD TRAUMA OR EPILEPSY | WARNER-LAMBERT COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |