Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 5/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377966 | 0.94 | MTTP (0.41) | MTTPALDH1A1HPGDAVPR2AVPR1A | |
| SCHEMBL7369305 | 0.93 | F10 (0.39) | KDM4EALDH1A1HPGDF10AVPR2 | |
| SCHEMBL7519200 | 0.92 | MTTP (0.42) | MTTPKDM4EALDH1A1HPGDF10 | |
| SCHEMBL7371186 | 0.92 | AVPR2 (0.42) | MTTPALDH1A1AVPR2AVPR1AAVPR1B | |
| SCHEMBL7372866 | 0.90 | MAPT (0.42) | KDM4EALDH1A1HPGDF10AVPR2 | |
| SCHEMBL7376314 | 0.88 | MTTP (0.42) | MTTPKDM4EALDH1A1HPGD | |
| SCHEMBL7374507 | 0.88 | MAPT (0.43) | MTTPKDM4EALDH1A1HPGD | |
| SCHEMBL7369597 | 0.87 | MEN1 (0.39) | ALDH1A1HPGDAVPR2AVPR1AAVPR1B | |
| SCHEMBL7372148 | 0.87 | MTTP (0.44) | MTTPALDH1A1HPGDAVPR2AVPR1A | |
| SCHEMBL7749369 | 0.87 | AVPR2 (0.49) | MTTPALDH1A1HPGDAVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |