SCHEMBL737007

SCHEMBL737007

NCCNCCCc1ccccc1

nearest known ligand 0.83

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 7/20 0.83
MAOA P21397 1/20 0.61
DRD2 P14416 1/20 0.61
DRD4 P21917 1/20 0.61
DRD3 P35462 1/20 0.61
KCNH2 Q12809 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9819821 0.98 SIGMAR1 (0.79) SIGMAR1MAOADRD2DRD4DRD3
SCHEMBL10934664 0.94 SIGMAR1 (0.79) SIGMAR1MAOADRD2DRD4DRD3
SCHEMBL4953212 0.94 SIGMAR1 (0.80) SIGMAR1MAOA
SCHEMBL14420295 0.92 SIGMAR1 (0.84) SIGMAR1MAOA
SCHEMBL4254894 0.91 SIGMAR1 (1.00) SIGMAR1DRD2DRD4DRD3KCNH2
SCHEMBL3624033 0.89 SIGMAR1 (0.72) SIGMAR1MAOAKCNH2
SCHEMBL2538905 0.89 SIGMAR1 (0.95) SIGMAR1DRD2DRD4DRD3KCNH2
SCHEMBL10936918 0.88 SIGMAR1 (0.77) SIGMAR1MAOA
SCHEMBL13937395 0.87 SIGMAR1 (0.69) SIGMAR1MAOAKCNH2
Hydrochloric Acid SCHEMBL4696714 0.87 SIGMAR1 (0.69) SIGMAR1MAOAKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5948419-A AQUEOUS EMULSION POLYMERIC BINDER; SILANE COUPLING AGENT THE DUMAIS COMPANIES, L.L.C. (US) 1999-09-07 US claimed
WO-1999033432-A1 AQUEOUS-BASED NAIL COATING COMPOSITION THE DUMAIS COMPANIES, L.L.C. (US) 1999-07-08 WO claimed
JP-10010894-A None JP disclosed
CN-107829094-B High temperature resistant corrosion inhibitor and preparation method thereof 中国石油化工股份有限公司 2019-10-11 CN disclosed
CN-109689671-A The modified polymer in surface 北卡罗来纳州大学 2019-04-26 CN disclosed
CN-109689670-A The modified polymer in surface 北卡罗来纳州大学 2019-04-26 CN disclosed
CN-106220994-B A kind of high intensity PP-RCT anti-flaming tubular products and preparation method 刘志光 2018-06-01 CN disclosed
CN-107829094-A Sulfur resistive high temperature resistant corrosion inhibitor and preparation method thereof 中国石油化工股份有限公司 2018-03-23 CN disclosed
CN-107531909-A The method of functionalized polymeric 阿克苏诺贝尔化学品国际有限公司 2018-01-02 CN disclosed
CN-107531825-A Polymer-modified method 阿克苏诺贝尔化学品国际有限公司 2018-01-02 CN disclosed
CN-103242701-B Recording material 精工爱普生株式会社 2017-04-26 CN disclosed
JP-H1010894-A FUSER SYSTEM MEMBER XEROX CORP 1998-01-16 JP disclosed
WO-1997010177-A1 PROCESS FOR THE PRODUCTION OF ORGANOFUNCTIONALISED AEROGELS HOECHST RESEARCH & TECHNOLOGY DEUTSCHLAND GMBH & CO. KG (DE) 1997-03-20 WO disclosed
WO-1995021262-A1 PROCESS FOR SOLID PHASE GLYCOPEPTIDE SYNTHESIS THE SCRIPPS RESEARCH INSTITUTE (US) 1995-08-10 WO disclosed
US-5369017-A Process for solid phase glycopeptide synthesis THE SCRIPPS RESEARCH INSTITUTE (US) 1994-11-29 US disclosed
US-4987132-A PLATELET ACTIVATING FACTOR ANTAGONISTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1991-01-22 US disclosed
EP-0396156-A1 Method of manufacturing a membrane for an electrochemical sensor MILES INC. (US) 1990-11-07 EP disclosed
US-4863831-A Photosensitive lithographic plate requiring no dampening water having a gelatin primer layer FUJI PHOTO FILM CO., LTD. (JP) 1989-09-05 US disclosed
US-4861698-A HARDENED GELATIN, SILICONE RUBBER FUJI PHOTO FILM CO., LTD. (JP) 1989-08-29 US disclosed
EP-0279681-A2 Saturated heterocyclic carboxamide derivatives YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1988-08-24 EP disclosed