Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 9/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370240 | 1.00 | S1PR1 (0.48) | S1PR1S1PR3MEN1KMT2AHPGD | |
| SCHEMBL7375339 | 0.90 | HDAC1 (0.43) | MEN1KMT2AAKR1B1CYSLTR2CYSLTR1 | |
| SCHEMBL7375341 | 0.90 | HDAC1 (0.43) | MEN1KMT2AAKR1B1CYSLTR2CYSLTR1 | |
| SCHEMBL7293144 | 0.77 | APP (0.51) | S1PR1S1PR3MEN1KMT2AFFAR1 | |
| SCHEMBL450848 | 0.77 | HRH3 (0.52) | S1PR1S1PR3MEN1KMT2AFFAR1 | |
| SCHEMBL7293139 | 0.77 | APP (0.51) | S1PR1S1PR3MEN1KMT2AFFAR1 | |
| SCHEMBL450847 | 0.77 | HRH3 (0.52) | S1PR1S1PR3MEN1KMT2AFFAR1 | |
| SCHEMBL451122 | 0.76 | S1PR1 (0.61) | S1PR1S1PR3MEN1KMT2AHPGD | |
| SCHEMBL451121 | 0.76 | S1PR1 (0.61) | S1PR1S1PR3MEN1KMT2AHPGD | |
| SCHEMBL7284483 | 0.74 | S1PR1 (0.48) | S1PR1S1PR3MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461677-B1 | Novel thiazolidine derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-04-16 | — | — | EP | claimed |
| EP-0461677-A1 | Novel thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |