Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.50 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373471 | 0.96 | ALDH1A1 (0.55) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL7371473 | 0.88 | KMT2A (0.50) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL7375943 | 0.88 | KDM4E (0.52) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL7367419 | 0.87 | KMT2A (0.54) | KMT2AALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL7370820 | 0.86 | CACNA1F (0.55) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL7372404 | 0.85 | ALDH1A1 (0.55) | KMT2AALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL7377172 | 0.85 | CACNA1F (0.54) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL7372045 | 0.83 | ALDH1A1 (0.54) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL7372518 | 0.83 | ALDH1A1 (0.53) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL7372403 | 0.81 | KMT2A (0.48) | KMT2AALDH1A1SMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706517-B1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL IND LTD (JP) | 1998-10-21 | — | — | EP | disclosed |
| WO-1995001343-A1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |