Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 15/20 | 0.34 |
| ▸ | ITGAV | P06756 | 15/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525562 | 0.73 | ITGB3 (0.39) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL7910284 | 0.73 | ITGB3 (0.39) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL7079739 | 0.72 | GAA (0.47) | MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7545624 | 0.70 | MEN1 (0.39) | ITGB3ITGAVITGA2BMEN1ALDH1A1 | |
| SCHEMBL7441028 | 0.65 | ITGB3 (0.45) | ITGB3ITGAVITGA2BCACNA1GCACNA1H | |
| SCHEMBL7399894 | 0.64 | ITGB1 (0.41) | ITGB3ITGAVITGA2BCACNA1GCACNA1H | |
| SCHEMBL7798122 | 0.64 | HSD17B3 (0.39) | ITGB3ITGAVITGA2BALDH1A1 | |
| SCHEMBL7338319 | 0.63 | PARP1 (0.44) | ITGB3ITGAVITGA2BALDH1A1 | |
| SCHEMBL7544674 | 0.63 | ITGB3 (0.39) | ITGB3ITGAVITGA2B | |
| SCHEMBL7441878 | 0.61 | ITGB3 (0.53) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767792-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | claimed |
| EP-0767792-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-04-16 | — | — | EP | claimed |
| WO-1996000730-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | claimed |