Aminodiphenylmethane

Aminodiphenylmethane

SCHEMBL7370499

NC(c1ccccc1)c1ccccc1.N[C@@H](Cc1cccc2ccccc12)C(=O)O

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.54
KDM4E B2RXH2 1/20 0.54
MEN1 O00255 1/20 0.54
LMNA P02545 1/20 0.54
MPO P05164 1/20 0.54
TSHR P16473 1/20 0.54
BLM P54132 1/20 0.54
PMP22 Q01453 1/20 0.54
KMT2A Q03164 1/20 0.54
HIF1A Q16665 1/20 0.54
CTNNB1 P35222 1/20 0.52
SLC1A3 P43003 1/20 0.50
SLC1A2 P43004 1/20 0.50
SLC1A1 P43005 1/20 0.50
TDP1 Q9NUW8 1/20 0.49
NOS3 P29474 2/20 0.48
NOS1 P29475 2/20 0.48
NOS2 P35228 2/20 0.48
ALPI P09923 1/20 0.47
PKM P14618 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29482763 0.92 CTNNB1 (0.59) MAPTKDM4EMEN1LMNAMPO
SCHEMBL29397866 0.92 CTNNB1 (0.59) MAPTKDM4EMEN1LMNAMPO
SCHEMBL29397858 0.92 CTNNB1 (0.59) MAPTKDM4EMEN1LMNAMPO
SCHEMBL660499 0.92 CTNNB1 (0.59) MAPTKDM4EMEN1LMNAMPO
SCHEMBL93515 0.92 CTNNB1 (0.59) MAPTKDM4EMEN1LMNAMPO
SCHEMBL93516 0.92 CTNNB1 (0.59) MAPTKDM4EMEN1LMNAMPO
SCHEMBL1025267 0.92 CTNNB1 (0.59) MAPTKDM4EMEN1LMNAMPO
Hydrochloric Acid SCHEMBL29400669 0.91 CTNNB1 (0.58) MAPTKDM4EMEN1LMNAMPO
Hydrochloric Acid SCHEMBL29370597 0.91 CTNNB1 (0.58) MAPTKDM4EMEN1LMNAMPO
Hydrochloric Acid SCHEMBL5967395 0.91 CTNNB1 (0.58) MAPTKDM4EMEN1LMNAMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0956296-A2 SOMATOSTATIN ANTAGONISTS SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 1999-11-17 EP disclosed
WO-1998024807-A2 SOMATOSTATIN ANTAGONISTS SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A. (S.C.R.A.S.) (FR) 1998-06-11 WO disclosed