Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368453 | 0.80 | F2 (0.47) | F2F10 | |
| SCHEMBL7361749 | 0.74 | F2 (0.48) | F2 | |
| SCHEMBL7365971 | 0.74 | F2 (0.54) | F2F10 | |
| SCHEMBL7362729 | 0.74 | F2 (0.46) | F2 | |
| SCHEMBL7719627 | 0.73 | F2 (0.76) | F2 | |
| SCHEMBL7361942 | 0.70 | F2 (0.42) | F2F10 | |
| SCHEMBL7364331 | 0.67 | F2 (0.53) | F2 | |
| SCHEMBL7368343 | 0.65 | F2 (0.56) | F2F10 | |
| SCHEMBL7368115 | 0.64 | F2 (0.43) | F2F10 | |
| SCHEMBL7370788 | 0.60 | F2 (0.45) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259506-A1 | PYRAZINONE THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001038323-A1 | PYRAZINONE THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2001-05-31 | — | — | WO | disclosed |