Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752657 | 0.88 | PRSS1 (0.61) | MAPT | |
| Iodide SCHEMBL7752650 | 0.87 | PRSS1 (0.59) | MAPT | |
| Hydrochloric Acid SCHEMBL7302913 | 0.87 | PRSS1 (0.62) | MAPT | |
| SCHEMBL9042605 | 0.86 | L3MBTL1 (0.59) | MAPTSMN1; SMN2L3MBTL1BRD4CYSLTR2 | |
| SCHEMBL3811266 | 0.85 | L3MBTL1 (0.59) | MAPTSMN1; SMN2L3MBTL1BRD4CYSLTR2 | |
| SCHEMBL3267566 | 0.84 | BRD4 (0.54) | MAPTSMN1; SMN2L3MBTL1BRD4CYSLTR2 | |
| SCHEMBL6937314 | 0.84 | MEN1 (0.62) | MAPTSMN1; SMN2L3MBTL1BRD4CYSLTR2 | |
| SCHEMBL3814672 | 0.84 | L3MBTL1 (0.63) | MAPTSMN1; SMN2L3MBTL1BRD4CYSLTR2 | |
| Hydrochloric Acid SCHEMBL31742267 | 0.83 | BRD4 (0.53) | MAPTSMN1; SMN2L3MBTL1BRD4CYSLTR2 | |
| SCHEMBL6832520 | 0.83 | PARP10 (0.61) | PARP10MAPTSMN1; SMN2L3MBTL1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2629094-A1 | Optical biosensors | CARNEGIE MELLON UNIVERSITY (US) | 2013-08-21 | — | — | EP | disclosed |
| US-5907068-A | TRIFLUOROMETHYLSUBSTITUTED COMPOUND INCLUDED IN PEPTIDES | ZENECA INC. (US) | 1999-05-25 | — | — | US | disclosed |
| US-5726158-A | INHIBITORS OF HUMAN LEUKOCYTE ELASTASE USEFUL IN TREATING TISSUE DEGENERATIVE DISEASES; TRIFLUOROMETHYL KETONE SUBSTITUTED DI-, TRI-, AND TETRA-PEPTIDE DERIVATIVES | ZENECA INC. (US) | 1998-03-10 | — | — | US | disclosed |
| US-5414132-A | Peptide intermediates | ZENECA INC. (US) | 1995-05-09 | — | — | US | disclosed |
| US-5194588-A | Inhibitors of human leukocyte elastase, di-, tri- and tetra-peptides | ICI AMERICAS INC. (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0189305-B1 | PEPTIDE DERIVATIVES | ICI AMERICAS INC. (US) | 1992-07-29 | — | — | EP | disclosed |
| US-5055450-A | Di-, tri- and tetrapeptides as inhibitors of human leukocyte elastase | ICI AMERICAS INC. (US) | 1991-10-08 | — | — | US | disclosed |
| US-4910190-A | Containing a nitrogen containing heterocycle ring structure | ICI AMERICAS INC. (US) | 1990-03-20 | — | — | US | disclosed |
| EP-0189305-A2 | Peptide derivatives | ICI AMERICAS INC. (US) | 1986-07-30 | — | — | EP | disclosed |